NSJ Bioreagents

Connexin 26 Antibody / GJB2 (Antigen affinity purified)

Product Code:
 
NSJ-RQ6770
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Connexin 26 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of 1) rat liver, 2) rat kidney, 3) mouse liver and 4) mouse kidney tissue lysate with Connexin 26 antibody. Predicted molecular weight: ~26 kDa.
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Western blot testing of 1) rat liver, 2) rat kidney, 3) mouse liver and 4) mouse kidney tissue lysate with Connexin 26 antibody. Predicted molecular weight: ~26 kDa.

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CodeSizePrice
NSJ-RQ6770-100ug100ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Connexin 26 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Connexin 26 (CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5% identity with rat Cx26. connexin 26 (GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene (GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids A88-T137) was used as the immunogen for the Connexin 26 antibody.
Limitation:
This Connexin 26 antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P29033

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