NSJ Bioreagents

CD25 Antibody / IL2RA

Product Code:
 
NSJ-V4086
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
IL2RA/4375R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the CD25 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 1
SDS-PAGE analysis of purified, BSA-free CD25 antibody (clone IL2RA/4375R) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free CD25 antibody (clone IL2RA/4375R) as confirmation of integrity and purity.

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CodeSizePrice
NSJ-V4086-20UG20 ug£264.00
Quantity:
NSJ-V4086-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Description:
CD25, or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been isolated and determined to result from extracellular proteolysis. CD25 (the p55 chain of the interleukin-2 receptor) is a marker of activation for a number of cell types, including T cells, B cells, and macrophages. It also appears to be a reliable immunohistochemical marker for the discrimination of neoplastic from normal/reactive mast cells, with potential as a diagnostic tool in systemic mastocytosis. CD25 is also expressed on hairy cell leukemia.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant partial protein (within amino acids 1-250) from the human protein was used as the immunogen for the CD25 antibody.
Limitation:
This CD25 antibody is available for research use only.
Localization:
Cell surface,
Purity:
Protein A/G affinity
Uniprot #:
P01589

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