NSJ Bioreagents

LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF1 alpha

Product Code:
 
NSJ-V5057SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LEF1/8629R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the Lymphoid enhancer-binding factor 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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IHC staining of FFPE analysis of human tonsil tissue with Lymphoid enhancer-binding factor 1 antibody (clone LEF1/8629R). Strong nuclear staining of non-germinal center cells observed. Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM
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IHC staining of FFPE analysis of human tonsil tissue with Lymphoid enhancer-binding factor 1 antibody (clone LEF1/8629R). Strong nuclear staining of non-germinal center cells observed. Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM

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NSJ-V5057SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells.Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant partial protein sequence (within amino acids 1-300) from the human protein was used as the immunogen for the Lymphoid enhancer-binding factor 1 antibody.
Limitation:
This Lymphoid enhancer-binding factor 1 antibody is available for research use only.
Localization:
Nucleus
Purity:
Protein A/G affinity
Uniprot #:
Q9UJU2

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