TargetMol

JB002

Product Code:
 
TAR-T72023
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72023-1mg1mg£127.00
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TAR-T72023-5mg5mg£209.00
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TAR-T72023-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T72023-10mg10mg£294.00
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TAR-T72023-25mg25mg£523.00
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TAR-T72023-50mg50mg£702.00
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TAR-T72023-100mg100mg£946.00
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TAR-T72023-500mg500mg£1,821.00
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This product comes from: United States.
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Further Information

Bioactivity:
JB002 is a myosin II inhibitor, with an IC 50 of ≤10 uM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy .
CAS:
30408-07-2
Formula:
C18H15NO3
Molecular Weight:
293.32
Pathway:
Cytoskeletal Signaling
Purity:
0.9902
SMILES:
OC=1C=2C(OC(=O)C1\C(=N\CC3=CC=CC=C3)\C)=CC=CC2
Target:
Myosin

References

Smith JD, et al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2023;247:115008. Brawley J, et al. Synthesis and Evaluation of 4-Hydroxycoumarin Imines as Inhibitors of Class II Myosins. J Med Chem. 2020;63(19):11131-11148.