TargetMol

SLC26A3-IN-1

Product Code:
 
TAR-T72054
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T72054-1mg1mg£227.00
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Quantity:
TAR-T72054-5mg5mg£416.00
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TAR-T72054-10mg10mg£581.00
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TAR-T72054-25mg25mg£863.00
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Quantity:
TAR-T72054-50mg50mg£1,163.00
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Quantity:
TAR-T72054-100mg100mg£1,540.00
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Quantity:
TAR-T72054-500mg500mg£3,026.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestinal absorption of chloride and oxalate, and is associated with chloride-losing diarrhea.
CAS:
307552-53-0
Formula:
C23H18O4
Molecular Weight:
358.39
Pathway:
Metabolism
Purity:
0.9891
SMILES:
O=C(O)C1=C(OC=2C=CC(OCC=3C=CC=CC3C)=CC21)C=4C=CC=CC4
Target:
transporter

References

Cil O, et al. Small molecule inhibitors of intestinal epithelial anion exchanger SLC26A3 (DRA) with a luminal, extracellular site of action. Eur J Med Chem. 2023;249:115149.