TargetMol

BAA473

Product Code:
 
TAR-T10447
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1].
CAS:
T10447
Formula:
C36H62O5
Molecular Weight:
574.87
Purity:
0.98
SMILES:
C[C@@H]([C@H]([C@@]1(C)[C@@H]2O)CC[C@@]1([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C2=O)CCC(OCCCCCCCCCCCC)=O

Documents

References

Alimov I, et al. Bile acid analogues are activators of pyrin inflammasome. J Biol Chem. 2019 Mar 8;294(10):3359-3366.