TargetMol

Bisindolylmaleimide III

Product Code:
 
TAR-T77628
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77628-5mg5mg£128.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T77628-1mL1 mL * 10 mM (in DMSO)£133.00
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Quantity:
TAR-T77628-10mg10mg£164.00
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Quantity:
TAR-T77628-25mg25mg£227.00
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Quantity:
TAR-T77628-50mg50mg£303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T77628-100mg100mg£415.00
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Quantity:
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.
CAS:
137592-43-9
Molecular Weight:
384.43
Pathway:
Chromatin/Epigenetic|Cytoskeletal Signaling
Purity:
0.98
SMILES:
O=C1NC(=O)C(C2=CN(C=3C=CC=CC23)CCCN)=C1C4=CNC=5C=CC=CC54
Target:
PKC

Documents

References

Brehmer D, et al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500. Saito Y, et al. Role of ecto-kinase in phorbol ester-enhanced growth hormone-binding protein release from human IM-9 cells. Mol Cell Endocrinol. 1999 Jun 25;152(1-2):65-72.