TargetMol

Tr-PEG2-OH

Product Code:
 
TAR-T17149
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Tr-PEG2-OH is a PEG-based PROTAC linker utilized in PROTAC synthesis[1]. It also serves as a non-cleavable 2-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[2].
CAS:
105589-77-3
Formula:
C23H24O3
Molecular Weight:
348.43
Purity:
0.98
SMILES:
OCCOCCOC(C=1C=CC=CC1)(C=2C=CC=CC2)C=3C=CC=CC3

References

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.