TargetMol

N4Py

Product Code:
 
TAR-T25844
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T25844-100mg100mgEnquire
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TAR-T25844-500mg500mgEnquire
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Further Information

Bioactivity:
N4Py is a good synthetic mimic of the Bleomycins (BLMs), which are a family of natural antibiotics used clinically in the treatment of certain cancers.
CAS:
167695-87-6
Molecular Weight:
367.45
Purity:
0.98
SMILES:
N=1C=CC=CC1CN(CC2=NC=CC=C2)C(C3=NC=CC=C3)C4=NC=CC=C4

References

Chen PY, Tseng TH. A Switch from Mechanistic Competition Mediated by a Coordination between Temperature and Concentration Effects in the Oxidation Reaction of [FeII(N4Py/TPA)](OTf)2. Chemistry. 2018 Jun 11. doi: 10.1002/chem.201801028. [Epub ahead of print] PubMed PMID: 29889323. Geersing A, S?gaud N, van der Wijst MGP, Rots MG, Roelfes G. Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py. Inorg Chem. 2018 Jun 19. doi: 10.1021/acs.inorgchem.8b00714. [Epub ahead of print] PubMed PMID: 29916702. Draksharapu A, Rasheed W, Klein JEMN, Que L Jr. Facile and Reversible Formation of Iron(III)-Oxo-Cerium(IV) Adducts from Nonheme Oxoiron(IV) Complexes and Cerium(III). Angew Chem Int Ed Engl. 2017 Jul 24;56(31):9091-9095. doi: 10.1002/anie.201704322. Epub 2017 Jun 27. PubMed PMID: 28598024; PubMed Central PMCID: PMC5598155. Chen J, Unjaroen D, Stepanovic S, van Dam A, Gruden M, Browne WR. Selective Photo-Induced Oxidation with O(2) of a Non-Heme Iron(III) Complex to a Bis(imine-pyridyl)iron(II) Complex. Inorg Chem. 2018 Apr 16;57(8):4510-4515. doi: 10.1021/acs.inorgchem.8b00187. Epub 2018 Mar 30. PubMed PMID: 29601196; PubMed Central PMCID: PMC5906753.