TargetMol

Teicoplanin aglycone

Product Code:
 
TAR-T26256
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T26256-100mg100mgEnquire
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TAR-T26256-500mg500mgEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Teicoplanin aglycone is an antibacterial glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Enterococcus faecalis and methicillin-resistant Staphylococcus aureus.
CAS:
89139-42-4
Molecular Weight:
1198.93
Purity:
0.98
SMILES:
[H][C@@]12Cc3ccc(Oc4cc5cc(Oc6ccc(cc6Cl)[C@@H](O)[C@]6([H])NC(=O)[C@]([H])(NC(=O)[C@]5([H])NC(=O)[C@@]([H])(NC1=O)c1cc(O)cc(Oc5cc(ccc5O)[C@@H](N)C(=O)N2)c1)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC6=O)C(O)=O)c4O)c(Cl)c3

Documents

References

Ravichandran S, Collins JR, Singh N, W Wainer I. A molecular model of the enantioselective liquid chromatographic separation of (R,S)-ifosfamide and its N-dechloroethylated metabolites on a teicoplanin aglycon chiral stationary phase. J Chromatogr A. 2012 Dec 21;1269:218-25. doi: 10.1016/j.chroma.2012.08.019. Epub 2012 Aug 10. PubMed PMID: 22917979; PubMed Central PMCID: PMC3513553. Tollas S, Bereczki I, Sipos A, R?th E, Batta G, Dar?czi L, K?ki S, Ostorh?zi E, Rozgonyi F, Herczegh P. Nano-sized clusters of a teicoplanin ?-aglycon-fullerene conjugate. Synthesis, antibacterial activity and aggregation studies. Eur J Med Chem. 2012 Aug;54:943-8. doi: 10.1016/j.ejmech.2012.06.054. Epub 2012 Jul 4. PubMed PMID: 22795664. Bick MJ, Banik JJ, Darst SA, Brady SF. Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone. Biochemistry. 2010 May 18;49(19):4159-68. doi: 10.1021/bi100150v. PubMed PMID: 20361791; PubMed Central PMCID: PMC2888265. Gonnella NC, Grinberg N, Mcloughlin M, Choudhary O, Fandrick K, Ma S. Three-dimensional structure of cyclic antibiotic teicoplanin aglycone using NMR distance and dihedral angle restraints in a DMSO solvation model. Magn Reson Chem. 2015 Oct;53(10):829-35. doi: 10.1002/mrc.4279. Epub 2015 Jul 1. PubMed PMID: 26138046.