TargetMol

Boc-bipiperidine-ethynylbenzoic acid

Product Code:
 
TAR-T39842
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Boc-bipiperidine-ethynylbenzoic acid is an alkyl/ether-based PROTAC linker commonly employed for the synthesis of ARD-61.
CAS:
2308497-81-4
Formula:
C24H32N2O4
Molecular Weight:
412.53
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)N1CCC(CC1)N1CCC(CC1)C#Cc1ccc(cc1)C(O)=O

References

Lijie Zhao, et al. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020 Oct;22(10):522-532.