FN14 (human):Fc (human) (rec.) (MultiPack)
Product Code:
AG-40B-0034
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This product comes from:
Switzerland.
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7-10 working days.
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Further Information
Alternate Names/Synonyms:
Tumor Necrosis Factor Receptor Superfamily Member 12A; FGF-inducible 14; Tweak-receptor; CD266; TNFRSF12A
1mg/ml after reconstitution.
32160000
<0.1EU/µg purified protein (LAL test; Lonza).
liquid
Lyophilized. Contains PBS.
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Protein. The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to mouse and human TWEAK. Purity: >95% (SDS-PAGE). TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK?Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
~35kDa (SDS-PAGE).
Q9NP84
Plastic Vial
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK?Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
>95% (SDS-PAGE)
The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.
HEK 293 cells
Binds to mouse and human TWEAK.
Fc
Non-hazardous
Other Proteins
12352202
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.