AdipoGen Life Sciences

RANK (mouse):Fc (human) (rec.)

Product Code:
 
AG-40B-0092
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Shipping:
 
Blue Ice
 

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CodeSizePrice
AG-40B-0092-C05050 ug£230.00
Quantity:
AG-40B-0092-30503 x 50 ug£450.00
Quantity:
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Further Information

Alternate Names/Synonyms:
TNFRSF11A; ODFR; Osteoclast Differentiation Factor Receptor; CD265
Biological Activity:
Inhibits mouse and human RANKL biological functions.
Concentration:
1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.01EU/µg purified protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to mouse and human RANKL. Purity: >95% (SDS-PAGE). RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
Molecular Weight:
~55kDa (SDS-PAGE)
NCBI, Uniprot Number:
O35305
Package Type:
Plastic Vial
Product Description:
RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
Purity:
>95% (SDS-PAGE)
Sequence:
Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1.
Source / Host:
HEK 293 cells
Specificity:
Binds to mouse and human RANKL.
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

References

RANKL signaling sustains primary tumor growth in genetically engineered mouse models of lung adenocarcinoma: J. Faget, et al.; J. Thoracic Oncol. 13, 387 (2017)