Irisin (rec.) (E. coli)

Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)

0.1mg/ml after reconstitution.

32160000

<0.1EU/µg purified protein (LAL test; Lonza).

liquid

Lyophilized from PBS or TRIS buffer (lot-dependent).

After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.

Protein. Irisin (human, aa 32-143 / mouse, aa 29-140) is untagged. Irisin has 100% identity between mouse, rat, monkey and human. Source: E. coli. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >95% (SDS-PAGE). Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

~12kDa

Q8NAU1

Plastic Vial

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

>95% (SDS-PAGE)

Irisin (human, aa 32-143 / mouse, aa 29-140) is untagged. Irisin has 100% identity between mouse, rat, monkey and human.

E. coli

no TAG

Non-hazardous

Other Proteins

12352202

Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.