CD279 [PD-1] (human)-muIg Fusion Protein (preservative free)
Code | Size | Price |
---|
ANC-549-820-25ug | 25 ug | £473.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Shipping:
BI
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Programmed Cell Death 1
EClass:
32160000
Form (Short):
liquid
Formulation:
50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl.
Handling Advice:
Avoid freeze/thaw cycles.
Labels - Conjugates:
Preservative Free
Long Description:
Protein. Liquid. 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. Human CD279 (PD-1; Programmed Cell Death 1) is a 55 kD Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses.
Package Type:
Plastic Vial
Product Description:
Human CD279 (PD-1; Programmed Cell Death 1) is a 55 kD Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses.
Purity:
>95% (SDS-PAGE)
Source / Host:
CHO cells
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at +4°C.
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