Chimerigen

IL-2 (rat) (rec.) (His)

Product Code:
 
CHI-RR-30002
Product Group:
 
Recombinant Proteins
Supplier:
 
Chimerigen
Regulatory Status:
 
RUO
Target Species:
 
Rat
Shipping:
 
BI
Storage:
 
-20°C
 

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CHI-RR-30002-C01010 ug£205.00
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Further Information

Alternate Names/Synonyms:
Interleukin-2; Aldesleukin
EClass:
32160000
Endotoxin:
<1EU/µg protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS (pH 7.4).
Handling Advice:
Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. Rat IL-2 (aa 21-155) is fused at the C-terminus to a His-tag. Source: E. coli. Endotoxin content: <1EU/µg protein (LAL test; Lonza). Lyophilized from 0.2µm-filtered solution in PBS (pH 7.4). Purity: >95% (SDS-PAGE). Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
NCBI, Uniprot Number:
NP_446288.1
Package Type:
Plastic Vial
Product Description:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Purity:
>95% (SDS-PAGE)
Sequence:
Rat IL-2 (aa 21-155) is fused at the C-terminus to a His-tag.
Source / Host:
E. coli
TAGs:
His
Transportation:
Non-hazardous
UNSPSC Category:
Interleukins
UNSPSC Number:
41116127
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.