ProSci

Slitrk4 Antibody

Product Code:
 
PSI-4473
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
1 / 3
Western blot analysis of Slitrk4 in mouse brain tissue lysate with Slitrk4 antibody at (A) 0.5 and (B) 1 μg/mL.
2 / 3
Immunohistochemistry of Slitrk4 in human brain tissue with Slitrk4 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of slitrk4 in human brain tissue with slitrk4 antibody at 20 μg/mL.
❮❯

Western blot analysis of Slitrk4 in mouse brain tissue lysate with Slitrk4 antibody at (A) 0.5 and (B) 1 μg/mL.
Immunohistochemistry of Slitrk4 in human brain tissue with Slitrk4 antibody at 2.5 μg/mL.
Immunofluorescence of slitrk4 in human brain tissue with slitrk4 antibody at 20 μg/mL.

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-4473-0.02mg0.02mg£150.00
Quantity:
PSI-4473-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Related Products
  • Show All

Further Information

Additional Names:
Slitrk4 Antibody: SLIT and NTRK-like protein 4
Application Note:
Slitrk4 antibody can be used for detection of Slitrk4 by Western blot at 0.5 and 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
Slitrk4 Antibody: SLIT and NTRK-like family 4 (Slitrk4) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk4 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
Background References:
  • Aruga J and Mikoshiba K. Identification and characterization of Slitrk, a novel transmembrane protein family controlling neurite outgrowth. Mol. Cell Neurosci.2003; 24:117-29.
  • Aruga J, Yokota N, and Mikoshiba K. Human SLITRK family genes: genomic organization and expression profiling in normal and brain tumor tissue. Gene2003; 315:87-94.
Buffer:
Slitrk4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Slitrk4 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Slitrk4.

The immunogen is located within amino acids 30 - 80 of Slitrk4.
NCBI Gene ID #:
139065
NCBI Official Name:
SLIT and NTRK-like family, member 4
NCBI Official Symbol:
SLITRK4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q8IW52
Protein GI Number:
46396931
Purification:
Slitrk4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
SPECIFICITY:
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Swissprot #:
Q8IW52
User NOte:
Optimal dilutions for each application to be determined by the researcher.