ProSci

NALP13 Antibody

Product Code:
 
PSI-5973
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
1 / 3
Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.
2 / 3
Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.
❮❯

Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.
Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.
Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.

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CodeSizePrice
PSI-5973-0.02mg0.02mg£150.00
Quantity:
PSI-5973-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
NALP13 Antibody: NOD14, PAN13, NALP13, CLR19.7, NOD14, NACHT, LRR and PYD domains-containing protein 13, Nucleotide-binding oligomerization domain protein 14
Application Note:
NALP13 antibody can be used for detection of NALP13 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
Background References:
  • Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
  • Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
Buffer:
NALP13 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.

The immunogen is located within amino acids 150 - 200 of NALP13.
NCBI Gene ID #:
126204
NCBI Official Name:
NLR family, pyrin domain containing 13
NCBI Official Symbol:
NLRP13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW72420
Protein GI Number:
119592826
Purification:
NALP13 Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
Q86W25
User NOte:
Optimal dilutions for each application to be determined by the researcher.