Further Information
ABCC11, ATP-binding cassette transporter MRP8, ATP-binding cassette, sub-family C (CFTR/MRP), member 11, EWWD, MRP8, WW, ATP-binding cassette protein C11, ATP-binding cassette, sub-family C, member 11, multi-resistance protein 8
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx. 125kDa band observed in Human Breast and Human Testis lysates (calculated MW of 150kDa according to NP_660187.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.5-1.5ug/ml. Primary incubation 1 hour at room temperature.Immunohistochemistry:Paraffin embedded Human Breast. Recommended concentration: 3.75ug/ml.
- Bortfeld M, Rius M, König J, Herold-Mende C, Nies AT, Keppler D. Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system. Neuroscience. 2006;137(4):1247-57
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
The immunogen for this antibody is: C-KVVEFDRPEVLRK
85320
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC11
Homo sapiens
Liquid
NP_115972.2, NP_660187.1
21729873
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Signal Transduction ,Cancer
This antibody is expected to recognize both reported isoforms (NP_115972.2; NP_660187.1). Reported variants represent identical protein (NP_115972.2; NP_149163.2).
Q96J66