ProSci

SNAI2 Antibody

Product Code:
 
PSI-27-822
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SNAI2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Human kidney.
2 / 3
3 / 3
Antibody used in IHC on Human Testis.
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Antibody used in IHC on Human kidney.
Antibody used in IHC on Human Testis.

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PSI-27-822-100ul100ul£662.00
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Further Information

Additional Names:
SNAI2, MGC10182, SLUG, SLUGH1, WS2D, SNAIL2
Application Note:
SNAI2 antibody can be used for detection of SNAI2 by ELISA at 1:312500. SNAI2 antibody can be used for detection of SNAI2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Mittal, M.K., (2008) Biochem. Biophys. Res. Commun. 372 (1), 30-34.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNAI2.
NCBI Gene ID #:
6591
NCBI Official Name:
snail family zinc finger 2
NCBI Official Symbol:
SNAI2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
NP_003059
Protein GI Number:
11276067
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
O43623
User NOte:
Optimal dilutions for each application to be determined by the researcher.