Further Information
DDX21, GUA, GURDB, RH-II/GU, RH-II/GuA
DDX21 antibody can be used for detection of DDX21 by ELISA at 1:12500. DDX21 antibody can be used for detection of DDX21 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
- Yang, H., et al., (2005) FEBS J. 272 (15), 3788-3802.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX21.
9188
DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX21
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
NP_004719
50659095
Antibody is purified by peptide affinity chromatography method.
Transcription ,Homeostasis
Q9NR30
Optimal dilutions for each application to be determined by the researcher.