ProSci

GluR1 Antibody

Product Code:
 
PSI-79-701
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from mouse brain and using GluR1 Antibody.
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Western blot analysis of lysed extracts from mouse brain and using GluR1 Antibody.

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PSI-79-701-0.1mg0.1mg£481.00
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Further Information

Additional Names:
GLUH1, GLUR1, GLURA, GluA1, HBGR1, GLR1, GLUH1, GRIA1, GluR-1, GluR-A
Application Note:
Western Blot: 1:500~1:1000
Background:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Emamian ES, et al. (2004) J Neurosci. 24 (7): 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GluR1 antibody was raised against a peptide sequence around aa. 831~835 (K-S-R-S-E) derived from Human GluR1 .
NCBI Gene ID #:
2890
NCBI Official Name:
glutamate receptor, ionotropic, AMPA 1
NCBI Official Symbol:
GRIA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_000818.2
Protein GI Number:
167001419
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody detects endogenous levels of total GluR1 protein.
Swissprot #:
P42261