Further Information
FCAS3, APLAID, PLC-IV, PLC-gamma-2, MEK6, MKK6, PRKMK6, SKK3, PLC-gamma2, Phospholipase C-gamma-2
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
- Kim YJ, et al. (2004) Mol Cell Biol 24: 9986-9999Humphries LA, et al. (2004) J Biol Chem 279 : 37651-37661Suzuki-Inoue K, et al. (2004) Biochem J 378 : 1023-1029Rodriguez R, et al. (2003) Biochem J 374 : 269-280
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
PLCgamma2 (Phospho-Tyr753) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 753 (S-L-Y (p) -D-V) derived from Human PLCγ2.
Phospho-Specific
5336
phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCG2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
150 kDa
NP_002652.2
117320537
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific,Neuroscience
This antibody detects endogenous level of PLCγ2 only when phosphorylated at tyrosine 753.
P16885