Further Information
JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA, CDHN, NCAD, JNK2
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
- Ferrer, et al. (2003) Neuropathology & Applied Neurobiology 29: 23 Zhonghong Guan, et al. (1999) J Biol Chem, Vol. 274: 36200-36206D. Margriet Ouwens1, et al. (2002) The EMBO Journal 21: 3782?3793, S Matsuyoshi1, et al. (2006) British Journal of Cancer 94: 532
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
5601
mitogen-activated protein kinase 9
MAPK9
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
46, 54 kDa
NP_001128516.1
205277412
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous level of total SAPK/JNK protein.
P45984///P53779