ProSci

SP1 Antibody

Product Code:
 
PSI-79-481
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
1 / 1
Western blot analysis of lysed extracts from 3T3 cells treated with starvation using SP1 (Phospho-Thr739).
❮❯

Western blot analysis of lysed extracts from 3T3 cells treated with starvation using SP1 (Phospho-Thr739).

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-79-481-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
TSFP1, TSFP1, Sp1 transcription factor
Application Note:
Western Blot: 1:500~1:1000
Background:
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Background References:
  • Thiesen HJ, et al. (1990) Nucleic Acids Res. 18 (11): 3203-9. Zutter MM, et al. (1997) Blood. 90 (2): 678-89. Lou Z, et al. (2005) Cancer Res. 65 (3): 1007-17
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SP1 (Phospho-Thr739) antibody was raised against a peptide sequence around phosphorylation site of threonine 739 (T-A-T (p) -P-S) derived from human SP1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
6667
NCBI Official Name:
Sp1 transcription factor
NCBI Official Symbol:
SP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
NP_612482.2
Protein GI Number:
38372901
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous levels of SP1 only when phosphorylated at threonine 739.
Swissprot #:
P08047