Antibody Clonality:
Polyclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CYP3A7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
CYP3A7, CP37, P450-HFLA, CYPIIIA7
CYP3A7 antibody can be used for detection of CYP3A7 by ELISA at 1:312500. CYP3A7 antibody can be used for detection of CYP3A7 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
CYP3A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
- Sim, S.C., (2005) Pharmacogenet. Genomics 15 (9), 625-631.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP3A7.
1551
cytochrome P450, family 3, subfamily A, polypeptide 7
CYP3A7
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
NP_000756
262290932
Antibody is purified by protein A chromatography method.
Membrane ,Signal Transduction
P24462
Optimal dilutions for each application to be determined by the researcher.