ProSci

AIRE Antibody

Product Code:
 
PSI-45-226
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
1 / 2
45-226 staining (0.05ug/ml) of HEK293 cell lysates. Untransfected (Lane 3) and transfected with Human AIRE (lane 4). Data kindly provided by Prof. P?rt Peterson, University of Tartu, Estonia.
2 / 2
❮❯

45-226 staining (0.05ug/ml) of HEK293 cell lysates. Untransfected (Lane 3) and transfected with Human AIRE (lane 4). Data kindly provided by Prof. P?rt Peterson, University of Tartu, Estonia.

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CodeSizePrice
PSI-45-226-0.1mg0.1mg£626.00
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Further Information

Additional Names:
AIRE, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) , AIRE1, APECED, APS1, APSI, PGA1 , autoimmune regulator (APECED protein), autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Appr. 60kDa in transfected HEK293 lysates (calculated MW of 57.7kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 ug/ml.Immunohistochemistry:In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This product was confirmed in IHC on fetal Pig Thymus (PMID: 24770647). Recommended concentration, 2.5ug/ml.
Background References:
  • Niki S, Oshikawa K, Mouri Y, Hirota F, Matsushima A, Yano M, Han H, Bando Y, Izumi K, Matsumoto M, Nakayama KI, Kuroda N, Matsumoto M. Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice. J Clin Invest. 2006 May 1;116(5):1292-1301. Epub 2006 Apr 20.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-KDVDLSQPRKGRKP
NCBI Gene ID #:
326
NCBI Official Name:
autoimmune regulator
NCBI Official Symbol:
AIRE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000374.1
Protein GI Number:
4557291
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
O43918