ProSci

KCNQ3 Antibody

Product Code:
 
PSI-42-090
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
 

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CodeSizePrice
PSI-42-090-0.1mg0.1mg£505.00
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Further Information

Additional Names:
KCNQ3, potassium voltage-gated channel, KQT-like subfamily, member 3, BFNC2, EBN2, KV7.3, potassium channel, voltage-gated, subfamily Q, member 3, potassium voltage-gated channel KQT-like protein 3
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave an approx. 23kDa band in Human Brain (Cerebral Cortex, Amygdala, Hippocampus) lysates after 0.3ug/ml antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 96.7kDa according to NP_004510.1. The 23kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. J Biol Chem. 2007 Apr 20;282(16):12135-42.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Pig
Immunogen:
The immunogen for this antibody is: C-SDSVWTPSNKPI
NCBI Gene ID #:
3786
NCBI Official Name:
potassium voltage-gated channel, KQT-like subfamily, member 3
NCBI Official Symbol:
KCNQ3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_004510.1
Protein GI Number:
4758630
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
Swissprot #:
O43525