ProSci

KCNQ5 Antibody

Product Code:
 
PSI-42-089
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
 

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PSI-42-089-0.1mg0.1mg£505.00
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Further Information

Additional Names:
KCNQ5, potassium voltage-gated channel, KQT-like subfamily, member 5, Kv7.5, OTTHUMP00000016729, OTTHUMP00000064152, OTTHUMP00000064153, potassium channel protein
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Preliminary experiments gave an approx. 22kDa band in Human Brain (Hippocampus and Cerebral Cortex) and Human Skeletal Muscle lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 102kDa according to NP_062816.2. The 22kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Schuetz F, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. Am J Physiol Cell Physiol. 2008 Jul;295(1):C73-80.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Pig, Dog
Immunogen:
The immunogen for this antibody is: C-ESTDALSLPHVKLK
NCBI Gene ID #:
56479
NCBI Official Name:
potassium voltage-gated channel, KQT-like subfamily, member 5
NCBI Official Symbol:
KCNQ5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_062816.2, NP_001153602.1, NP_001153604.1, NP_1153605.1, NP_001153606.1
Protein GI Number:
28373065
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody is expected to cross-react with isoform 1, 2, 3, 4 and 5 (NP_062816.2; NP_001153602.1; NP_001153604.1; NP_1153605.1; NP_001153606.1).
Swissprot #:
Q9NR82