Chimerigen

IL-6R (mouse):Fc (mouse) (rec.)

Product Code:
 
CHI-MF-11006R
Product Group:
 
Recombinant Proteins
Supplier:
 
Chimerigen
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
BLUE ICE
Storage:
 
-20°C
 

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CHI-MF-11006R-C05050 ug£355.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Interleukin-6 Receptor Subunit alpha; IL6RA; CD126
Biological Activity:
Measured by its binding ability in a functional ELISA.
EClass:
32160000
Endotoxin:
<1EU/mg protein (LAL test; Lonza).
Form (Short):
solid
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS.
Handling Advice:
Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. The extracellular domain of mouse IL-6R (aa 20-357) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/µg protein (LAL test; Lonza). Lyophilized from 0.2µm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Molecular Weight:
~70-85kDa
NCBI, Uniprot Number:
CAA37810.1
Package Type:
Plastic Vial
Product Description:
Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Purity:
>98% (SDS-PAGE)
Sequence:
The extracellular domain of mouse IL-6R (aa 20-357) is fused to the N-terminus of the Fc region of mouse IgG2a.
Source / Host:
CHO cells
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Interleukins
UNSPSC Number:
41116127
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.