Meteorin-like (mouse) (rec.)

AdipoGen Life Sciences
Product Code: AG-40B-0149
Product Group: Recombinant Proteins
CodeSizePrice
AG-40B-0149-C01010 ug£150.00
Quantity:
AG-40B-0149-30103 x 10 ug£290.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Enzyme
Regulatory Status: RUO
Target Species: Mouse
Shipping:
Blue Ice
Storage:
-20°C

Further Information

Alternate Names/Synonyms:
Interleukin-41; IL-41; IL41; Metrnl; Subfatin; Cometin
Concentration:
0.1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.1EU/µg purified protein (LAL test).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Mouse meteorin-like (46-311) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >95% (SDS-PAGE). Meteorin-like (cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
Molecular Weight:
~35kDa (SDS-PAGE); ~ 40 kDA (Monomer) (SEC)
NCBI, Uniprot Number:
Q8VE43
Package Type:
Plastic Vial
Product Description:
Meteorin-like (interleukin-41; cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
Purity:
>95% (SDS-PAGE)
Sequence:
Mouse meteorin-like [IL-41] (46-311) is fused at the N-terminus to a FLAG®-tag.
Source / Host:
HEK 293 cells
TAGs:
FLAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

References

METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARdelta-dependent pathways in skeletal muscle of mice: T.W. Jung, et al.; Exper. Mol. Med. 50, 122 (2018)

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