AdipoGen Life Sciences

Jagged-2 (human):Fc (human) (rec.)

Product Code:
 
AG-40A-0155Y
Product Group:
 
Recombinant Proteins
Antibody Clonality:
 
Enzyme
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
-20°C
 

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AG-40A-0155Y-C01010 ug£217.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Protein Jagged-2; hJ2; JAG2
Concentration:
0.1mg/ml after reconstitution
EClass:
32160000
Endotoxin:
<0.1EU/µg purified protein (LAL test; Lonza).
Form (Short):
solid
Formulation:
Lyophilized. Contains PBS + 0.02 % CHAPS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS + 0.02 % CHAPS. Purity: >90% (SDS-PAGE). Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
Molecular Weight:
~150kDa (SDS-PAGE)
NCBI, Uniprot Number:
Q9Y219
Package Type:
Plastic Vial
Product Description:
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
Purity:
>90% (SDS-PAGE)
Sequence:
Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
Source / Host:
HEK 293 cells
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.