ProSci

Cardiotrophin-1 Recombinant Protein

Product Code:
 
PSI-40-290
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized Cardiotrophin-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Cardiotrophin-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As wit
 

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CodeSizePrice
PSI-40-290-0.002mg0.002mg£292.00
Quantity:
PSI-40-290-0.01mg0.01mg£415.00
Quantity:
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Further Information

Additional Names:
CT1, CT-1, Cardiotrophin-1
Background:
CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Recombinant Human CT-1 is a 21.5 kDa protein consisting of 201 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
NCBI Gene ID #:
1489
NCBI Official Name:
cardiotrophin 1
NCBI Official Symbol:
CTF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001136016.1
Protein GI Number:
216548056
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q16619

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