ProSci

VEGF165 Recombinant Protein

Product Code:
 
PSI-40-162
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized VEGF165 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e
 

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CodeSizePrice
PSI-40-162-0.002mg0.002mg£300.00
Quantity:
PSI-40-162-0.01mg0.01mg£428.00
Quantity:
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Further Information

Additional Names:
VPF, VEGF, MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF-A
Background:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0 - 8.0 ng/mL.
NCBI Gene ID #:
7422
NCBI Official Name:
vascular endothelial growth factor A
NCBI Official Symbol:
VEGFA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001028928.1
Protein GI Number:
76781487
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P15692-4

Documents