ProSci

Artemin Recombinant Protein

Product Code:
 
PSI-40-113
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized Artemin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Artemin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-40-113-0.005mg0.005mg£300.00
Quantity:
PSI-40-113-0.02mg0.02mg£428.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
EVN, NBN, ENOVIN, EVN, Artemin, Enovin
Background:
Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons. The functional human Artemin ligand is a disulfide-linked homodimer, of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits.
Biological Activity:
Biological Activity determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons.
NCBI Gene ID #:
9048
NCBI Official Name:
artemin
NCBI Official Symbol:
ARTN
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001129687.1
Protein GI Number:
209977029
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q5T4W7

Documents