ProSci

CTGFL Recombinant Protein

Product Code:
 
PSI-40-215
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized CTGFL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CTGFL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

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CodeSizePrice
PSI-40-215-0.005mg0.005mg£300.00
Quantity:
PSI-40-215-0.02mg0.02mg£428.00
Quantity:
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Further Information

Additional Names:
CCN5, CT58, CTGF-L, CCN5, CTGFL, UNQ228/PRO261, WNT1-inducible-signaling pathway protein 2, CCN family member 5, WISP-2
Background:
CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.
Biological Activity:
The ED50 was determined by its ability to inhibit IGF - II induced proliferation of MCF - 7 is between 10 - 20 ng/mL in the presence of 15 ng/mL of human IGF - II.
NCBI Gene ID #:
8839
NCBI Official Name:
WNT1 inducible signaling pathway protein 2
NCBI Official Symbol:
WISP2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003872.1
Protein GI Number:
4507923
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O76076

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