ProSci

ApoA-I Recombinant Protein

Product Code:
 
PSI-40-139
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized ApoA-I recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted ApoA-I is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
 

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CodeSizePrice
PSI-40-139-0.02mg0.02mg£300.00
Quantity:
PSI-40-139-0.1mg0.1mg£428.00
Quantity:
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Further Information

Additional Names:
Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Background:
ApoA-I is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol.? The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Recombinant human ApoA-I is a 28.2 kDa protein of 244 amino acid residues.
NCBI Gene ID #:
335
NCBI Official Name:
apolipoprotein A-I
NCBI Official Symbol:
APOA1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000030.1
Protein GI Number:
4557321
Purity:
Greater than 97% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P02647

Documents