ProSci

Flt3 Ligand Recombinant Protein

Product Code:
 
PSI-40-443
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
The lyophilized Flt3 Ligand recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Flt3 Ligand is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any pr
 

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CodeSizePrice
PSI-40-443-0.002mg0.002mg£300.00
Quantity:
PSI-40-443-0.01mg0.01mg£428.00
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Further Information

Additional Names:
Ly72L, Flt3lg, Flt3l, Fms-related tyrosine kinase 3 ligand, SL cytokine, Flt3 ligand
Background:
Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand has no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant murine Flt3-Ligand is a soluble 18.6 kDa protein consisting of 163 amino acid residues.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 5.0 - 8.0 ng/mL.
NCBI Gene ID #:
14256
NCBI Official Name:
FMS-like tyrosine kinase 3 ligand
NCBI Official Symbol:
Flt3l
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_038548.3
Protein GI Number:
227430331
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P49772

Documents