ProSci

IL-4 Recombinant Protein

Product Code:
 
PSI-40-433
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
The lyophilized IL-4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
 

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CodeSizePrice
PSI-40-433-0.005mg0.005mg£300.00
Quantity:
PSI-40-433-0.02mg0.02mg£428.00
Quantity:
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Further Information

Additional Names:
Il-4, BSF-1, Il-4, Interleukin-4, B-cell IgG differentiation factor, IL-4
Background:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of murine HT - 2 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
NCBI Gene ID #:
16189
NCBI Official Name:
interleukin 4
NCBI Official Symbol:
Il4
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_067258.1
Protein GI Number:
10946584
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P07750

Documents