ProSci

IL-1 alpha Recombinant Protein

Product Code:
 
PSI-40-461
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Rat
Storage:
 
The lyophilized IL-1 alpha recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-1 alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any prot
 

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CodeSizePrice
PSI-40-461-0.002mg0.002mg£300.00
Quantity:
PSI-40-461-0.01mg0.01mg£428.00
Quantity:
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Further Information

Additional Names:
IL-1 alpha, Interleukin-1 alpha, IL-1 alpha
Background:
IL-1β is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1α is a 17.7 kDa protein containing 155 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of murine D10S cells is < 0.005 ng/mL, corresponding to a specific activity of > 2 x 108 units/mg.
NCBI Gene ID #:
24493
NCBI Official Name:
interleukin 1 alpha
NCBI Official Symbol:
Il1a
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_058715.1
Protein GI Number:
8393593
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P16598

Documents