ProSci

CD16 Antibody [3G8] (FITC)

Product Code:
 
PSI-76-580
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
3G8
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-76-580-100tests100tests£597.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA, FCGR3A
Background:
The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Background References:
  • Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
  • Hayakawa, Y., Huntington, N. D., Nutt, S. L., Smyth, M. J. (2006). Functional subsets of mouse natural killer cells.Immunological reviews,214(1), 47-55.
  • Tittarelli, A., Mendoza-Naranjo, A., Faras, M., Guerrero, I., Ihara, F., Wennerberg, E., ... Salazar-Onfray, F. (2014). Gap Junction Intercellular Communications Regulate NK Cell Activation and Modulate NK Cytotoxic Capacity.The Journal of Immunology,192(3), 1313-1319.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
2214
NCBI Official Name:
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
NCBI Official Symbol:
FCGR3A
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII).
Swissprot #:
P08637
User NOte:
Optimal dilutions for each application to be determined by the researcher.