ProSci

CD66b Antibody [G10F5] (PE)

Product Code:
 
PSI-76-593
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgM, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
G10F5
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-593-100tests100tests£626.00
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Further Information

Additional Names:
CD67, CGM6, CD66b, NCA-95, CEACAM8
Background:
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family. CD66b is expressed on granulocytes, neutrophils, and eosinophils. It is reported that this molecule plays a role in regulating neutrophil activation and cellular adhesion. It was previously classified as CD67, but renamed CD66b in the Fifth HLDA Workshop.
Background References:
  • Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
  • Azuma, M., Ito, D., Yagita, H., Okumura, K., Phillips, J. H., Lanier, L. L., Somoza, C. (1993). B70 antigen is a second ligand for CTLA-4 and CD28.Nature,366(6450), 76-79.
  • Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
1088
NCBI Official Name:
carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Official Symbol:
CEACAM8
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family.
Swissprot #:
P31997
User NOte:
Optimal dilutions for each application to be determined by the researcher.