ProSci

CD27 Antibody [O323] (PE)

Product Code:
 
PSI-76-623
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
MouseIgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
O323
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-76-623-0.025mg0.025mg£307.00
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Further Information

Additional Names:
T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27
Background:
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a marker of memory B cells.
Background References:
  • Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
  • Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011). Differentiation of human peripheral blood Vdelta-1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.Blood,118(4), 992-1001.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
939
NCBI Official Name:
CD27 molecule
NCBI Official Symbol:
CD27
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology,Apoptosis
SPECIFICITY:
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells.
Swissprot #:
P26842
User NOte:
Optimal dilutions for each application to be determined by the researcher.