ProSci

SHP-1 (phospho Tyr564) Antibody

Product Code:
 
PSI-79-835
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from COS7 cells treated with EGF using SHP-1 (Phospho-Tyr564) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from COS7 cells treated with EGF using SHP-1 (Phospho-Tyr564) Antibody. The lane on the right is treated with the antigen-specific peptide.

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PSI-79-835-0.1mg0.1mg£488.00
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Further Information

Additional Names:
HCP, HCPH, PTN6, PTP1C, SHP1
Application Note:
Western Blot: 1:500~1:1000
Background:
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
Background References:
  • Yi T., Mol. Cell. Biol. 12:836-846(1992).
  • Shen S.H., Nature 352:736-739(1991).
  • Plutzky J., Proc. Natl. Acad. Sci. U.S.A. 89:1123-1127(1992).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SHP-1 (phospho Tyr564) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 564 (D-V-Y (p)-E-N) derived from Human SHP-1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5777
NCBI Official Name:
protein tyrosine phosphatase, non-receptor type 6
NCBI Official Symbol:
PTPN6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_002822.2
Protein GI Number:
18104989
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of SHP-1 only when phosphorylated at tyrosine 564.
Swissprot #:
P29350