ProSci

HS1 (phospho Tyr397) Antibody

Product Code:
 
PSI-79-926
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from JK cells (Lane 2), using HS1 (Phospho-Tyr397) Antibody. The lane on the left is treated with antigen-specific peptide.
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Western blot analysis of extracts from JK cells (Lane 2), using HS1 (Phospho-Tyr397) Antibody. The lane on the left is treated with antigen-specific peptide.

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PSI-79-926-0.1mg0.1mg£488.00
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Further Information

Additional Names:
HCLS1, LCKBP1, Hematopoietic cell- specific LYN substrate 1
Application Note:
Western Blot: 1:500~1:1000
Background:
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.
Background References:
  • Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).
  • Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
  • Ota T., Nat. Genet. 36:40-45(2004).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HS1 (phospho Tyr397) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 397 (G-D-Y (p)-E-E) derived from Human HS1 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3059
NCBI Official Name:
hematopoietic cell-specific Lyn substrate 1
NCBI Official Symbol:
HCLS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
NP_005326.2
Protein GI Number:
167234422
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of HS1 only when phosphorylated at tyrosine 397.
Swissprot #:
P14317