ProSci

CD27 Antibody [LG.3A10]

Product Code:
 
PSI-76-631
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Hamster
Antibody Isotype:
 
Armenian Hamster IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LG.3A10
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Storage:
 
The product should be stored undiluted at 4°C. Do not freeze.
 

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CodeSizePrice
PSI-76-631-0.5mg0.5mg£693.00
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Further Information

Additional Names:
S152, Tp55, Tnfrsf7, Cd27
Background:
The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.3A10 antibody is cross-reactive with human, mouse and rat CD27.
Background References:
  • Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005). Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175(12), 8415-8423.
  • Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
  • Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985). Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66(1), 64-68.
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
21940
NCBI Official Name:
CD27 antigen
NCBI Official Symbol:
Cd27
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/?g of the protein.
Research Area:
Immunology,Apoptosis,Functional Assays
SPECIFICITY:
The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily.
Swissprot #:
P41272
User NOte:
Optimal dilutions for each application to be determined by the researcher.