ProSci

CRMP-2 (phospho Ser522) Antibody

Product Code:
 
PSI-79-950
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from HuvEc cells (Lane 2), using CRMP-2 (Phospho-Ser522) Antibody. The lane on the left is treated with antigen-specific peptide.
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Western blot analysis of extracts from HuvEc cells (Lane 2), using CRMP-2 (Phospho-Ser522) Antibody. The lane on the left is treated with antigen-specific peptide.

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PSI-79-950-0.1mg0.1mg£488.00
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Further Information

Additional Names:
CRMP2, DPYL2, DRP2, ULIP-2
Application Note:
Western Blot: 1:500~1:1000
Background:
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Background References:
  • Goshima Y., Nature 376:509-514(1995).
  • Hamajima N., Gene 180:157-163(1996).
  • Kitamura K., DNA Res. 6:291-297(1999).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CRMP-2 (phospho Ser522) antibody was raised against a peptide sequence around phosphorylation site of Serine 522 (K-T-S (p)-P-A) derived from Human CRMP-2.
Modifications:
Phospho-Specific
NCBI Gene ID #:
1808
NCBI Official Name:
dihydropyrimidinase-like 2
NCBI Official Symbol:
DPYSL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
NP_001377.1
Protein GI Number:
3122051
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of DPYSL2 only when phosphorylated at serine 522.
Swissprot #:
Q16555