ProSci

TAL-1 (phospho Ser122) Antibody

Product Code:
 
PSI-79-923
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from JK cells (Lane 2), using TAL-1 (Phospho-Ser122) Antibody. The lane on the left is treated with antigen-specific peptide.
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Western blot analysis of extracts from JK cells (Lane 2), using TAL-1 (Phospho-Ser122) Antibody. The lane on the left is treated with antigen-specific peptide.

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PSI-79-923-0.1mg0.1mg£488.00
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Further Information

Additional Names:
SCL, TAL1, TCL5
Application Note:
Western Blot: 1:500~1:1000
Background:
TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.
Background References:
  • Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
  • Gregory S.G., Nature 441:315-321(2006).
  • Chen Q., J. Exp. Med. 172:1403-1408(1990).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p)-P-P) derived from Human TAL-1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
6886
NCBI Official Name:
T-cell acute lymphocytic leukemia 1
NCBI Official Symbol:
TAL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_001274276.1
Protein GI Number:
4507363
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.
Swissprot #:
P17542