ProSci

SIGLEC6 Recombinant Protein

Product Code:
 
PSI-96-692
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-692-0.1mg0.1mg£626.00
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Further Information

Additional Names:
SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Background References:
  • Takei Y., et al., 1997, Cytogenet. Cell Genet. 78:295-300.
  • Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.
Biological Activity:
Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
946
NCBI Official Name:
sialic acid binding Ig-like lectin 6
NCBI Official Symbol:
SIGLEC6
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
60.3 kDa
Protein Accession #:
AAH35359
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O43699

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