ProSci

PTHR1 Recombinant Protein

Product Code:
 
PSI-96-641
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-641-0.1mg0.1mg£597.00
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Further Information

Additional Names:
PTH1R, PTHR, PTHR1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Background References:
  • Johnston C.A., et al., 2008, Structure 16:1086-1094.
  • Pioszak A.A., et al., 2010, J. Biol. Chem. 285:12435-12444.
Biological Activity:
Measured by its binding ability in a functional ELISA. When rhPTH1R is used at 2 μg/mL, the concentration of biotinylated human PTHrP that produces 50% of the optimal binding response is found to be approximately 0. 1 - 0. 25 μg/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
5745
NCBI Official Name:
parathyroid hormone 1 receptor
NCBI Official Symbol:
PTH1R
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
19.3 kDa
Protein Accession #:
NP_000307
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q03431

Documents